The latest Spider-Man film has become the first pandemic-era film to gross more than $1 billion (£750 million) at the global box office.
In addition, Spider-Man: No Way Home was named the highest-grossing film of 2021.
According to media data analytics firm Comscore, Star Wars: The Rise of Skywalker was the most recent film to gross more than $1 billion.
Since the pandemic began two years ago, no other Hollywood film has come close to surpassing that box office milestone.
The latest Marvel Cinematic Universe picture grossed $1.05 billion worldwide over the weekend.
Even while the Omicron variety of Covid-19 has spread swiftly over the world, generating new concerns about indoor events, the Sony-Disney co-production reached its milestone less than two weeks after its premiere.
China, which is currently the world’s largest cinema market, has not yet seen the film.
Tom Holland reprises his role as Peter Parker in Spider-Man: No Way Home, featuring Zendaya as MJ and Benedict Cumberbatch as the wizard Doctor Strange.
Listen to our review of the film here.